Sudden Onset Rash – Friday Pop Quiz 1/21/2022
A 14-year-old female presents with the sudden onset of the skin findings pictured diffusely covering greater than 90% of her skin surface. The rash is accompanied by a high fever (40C) and elevated white blood cell count. What is the most likely cause of her condition?
A. ABCC6 mutation
B. Anti-FceR1 IgG antibodies
C. Anti-transglutaminase 3 antibodies
D. Deficiency of the IL-36 re …
A 14-year-old female presents with the sudden onset of the skin findings pictured diffusely covering greater than 90% of her skin surface. The rash is accompanied by a high fever (40C) and elevated white blood cell count. What is the most likely cause of her condition?
A. ABCC6 mutation
B. Anti-FceR1 IgG antibodies
C. Anti-transglutaminase 3 antibodies
D. Deficiency of the IL-36 re … Continue reading "Sudden Onset Rash – Friday Pop Quiz 1/21/2022"
A 23-year-old female presents with itchy and irritated rash in the image. The rash began in her late teens. She has a family history of similar rash in her mother. Which histocompatibility antigen is most likely in this patient?
A. HLA-Cw2
B. HLA-Cw6
C. HLA-B51
D. HLA-B27
E. HLA-Bw35
To find out the correct answer and read the explanation, click here.
Brought to yo … 
A 25 year-old previously healthy man presents with the skin findings shown, urethritis, and one month of peripheral arthritis. Which of the following is true regarding this condition?
A. Females and males are equally affected
B. A chronic deforming arthritis occurs in 20%
C. TNF-alpha inhibiting agents have no role in the treatment of this condition
D. Patients must have urethritis … 
This 17-year-old boy also reports dark urine, bilateral knee pain, and intermittent abdominal pain. Which of the following is true regarding this condition?
A. It is more common in adults than children
B. A DIF biopsy showing intravascular IgA deposition is diagnostic
C. It usually occurs after a respiratory tract infection
D. He has a high likelihood of developing permanent renal … 
Women’s Health recently wrote an article about four skin conditions that are commonly misdiagnosed. Why do primary care providers sometimes misdiagnose common skin conditions? What conditions are challenging for dermatologists to diagnose? What steps can a dermatologist take to make a differential diagnosis?
For expert advice, I contacted Steve Daveluy, MD, FAAD, associate professor and pr … 