Sonidegib Therapeutic Cheat Sheet
Basal cell carcinoma (BCC) is the most common human cancer. When curative surgery and radiotherapy are contraindicated, systemic agents targeting the hedgehog signaling pathway are invaluable options for this subset of adult patients with locally advanced BCC (laBCC). Vismodegib and sonidegib are oral options with similar efficacy and side effect profiles. With the absence of head-to-head comparis …
Basal cell carcinoma (BCC) is the most common human cancer. When curative surgery and radiotherapy are contraindicated, systemic agents targeting the hedgehog signaling pathway are invaluable options for this subset of adult patients with locally advanced BCC (laBCC). Vismodegib and sonidegib are oral options with similar efficacy and side effect profiles. With the absence of head-to-head comparis … 
On this Mnemonic Monday, we challenge you to remember the side effects of hedgehog inhibitors, vismodegib and sonidegib, with the following mnemonic:
MAD Weight loss
M=muscle spasm (72% of cases)
A=alopecia (64% of cases)
D= dysgeusia (55% of cases)
Weight loss= weight loss (45% of cases)
Click HERE to download or print your mnemonic card.
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