Ciclopirox Therapeutic Cheat Sheet
Ciclopirox is the only hydroxypyridone antifungal agent with a unique mechanism of action differentiating it from other antimycotic agents. Unlike the azole-antifungals which block the sterol synthesis in the fungal cell membrane, ciclopirox functions by chelating cations resulting in the degradation of fungal cells, as well as proposed anti-inflammatory properties. It is available in a variety of …
Ciclopirox is the only hydroxypyridone antifungal agent with a unique mechanism of action differentiating it from other antimycotic agents. Unlike the azole-antifungals which block the sterol synthesis in the fungal cell membrane, ciclopirox functions by chelating cations resulting in the degradation of fungal cells, as well as proposed anti-inflammatory properties. It is available in a variety of … 
Onychomycosis is an extremely common and difficult to treat condition. We have numerous oral and topical treatments in our therapeutic repertoire, but oral medication use is often limited by the risk of hepatotoxicity or drug interactions. Traditional topical lacquers, on the other hand, have limited efficacy due to their inability to adequately penetrate the nail plate. Efinaconazole is a newer t … 