Hedgehog Inhibitors in the Age of Immunotherapy
In the age of immunotherapy, is there a place for hedgehog inhibitors in cutaneous oncology?
ODAC Guest Advisor Dr. Vishal Patel says hedgehog inhibitors are even more important now. Dr. Patel spoke with Next Steps in Derm, in partnership with the ODAC Dermatology Conference, where he outlined scenarios in clinical treatment where hedgehog inhibitors make sense. Learn about the two approved m …
In the age of immunotherapy, is there a place for hedgehog inhibitors in cutaneous oncology?
ODAC Guest Advisor Dr. Vishal Patel says hedgehog inhibitors are even more important now. Dr. Patel spoke with Next Steps in Derm, in partnership with the ODAC Dermatology Conference, where he outlined scenarios in clinical treatment where hedgehog inhibitors make sense. Learn about the two approved m … Continue reading "Hedgehog Inhibitors in the Age of Immunotherapy"
INTRODUCTION
Periocular basal cell carcinoma (BCC) is the most common eyelid malignancy concomitant with ocular morbidity and quality of life impact.1,2 Orbital invasion occurs in 2% of cases and poses challenges for management.1,3 JDD authors highlight a multidisciplinary approach to the treatment of advanced periocular BCC.
CASE
JDD authors discuss a 56-year-old male who presente … 
Basal cell carcinoma (BCC) is the most common human cancer. When curative surgery and radiotherapy are contraindicated, systemic agents targeting the hedgehog signaling pathway are invaluable options for this subset of adult patients with locally advanced BCC (laBCC). Vismodegib and sonidegib are oral options with similar efficacy and side effect profiles. With the absence of head-to-head comparis … 
There are many procedural treatments that we have worked on finessing in dermatology, but for some patients with non-melanoma skin cancer, nonsurgical treatments should be discussed. We had the opportunity to review the strengths and weaknesses of nonsurgical treatment approaches for non-melanoma skin cancer and review the indications and future implications of these treatments at ODAC 2023 with D … 
On this Mnemonic Monday, we challenge you to remember the geographical areas and associated species known for NEW WORLD leishmaniasis transmission with the following mnemonic:
Let's Go Get Brazilian Blowouts in Mexico
Let's = “lutz” aka Lutzomya sandfly species responsible for transmitting new world leishmaniasis
Brazilian = L. braziliensis complex, leishmaniasis species commonly … 