Sonidegib Therapeutic Cheat Sheet
Basal cell carcinoma (BCC) is the most common human cancer. When curative surgery and radiotherapy are contraindicated, systemic agents targeting the hedgehog signaling pathway are invaluable options for this subset of adult patients with locally advanced BCC (laBCC). Vismodegib and sonidegib are oral options with similar efficacy and side effect profiles. With the absence of head-to-head comparis …
Basal cell carcinoma (BCC) is the most common human cancer. When curative surgery and radiotherapy are contraindicated, systemic agents targeting the hedgehog signaling pathway are invaluable options for this subset of adult patients with locally advanced BCC (laBCC). Vismodegib and sonidegib are oral options with similar efficacy and side effect profiles. With the absence of head-to-head comparis … 
There are many procedural treatments that we have worked on finessing in dermatology, but for some patients with non-melanoma skin cancer, nonsurgical treatments should be discussed. We had the opportunity to review the strengths and weaknesses of nonsurgical treatment approaches for non-melanoma skin cancer and review the indications and future implications of these treatments at ODAC 2023 with D … 
On this Mnemonic Monday, we challenge you to remember the geographical areas and associated species known for NEW WORLD leishmaniasis transmission with the following mnemonic:
Let's Go Get Brazilian Blowouts in Mexico
Let's = “lutz” aka Lutzomya sandfly species responsible for transmitting new world leishmaniasis
Brazilian = L. braziliensis complex, leishmaniasis species commonly … 
On this Mnemonic Monday, we challenge you to remember metabolic syndromes associated with trichorrhexis nodosa (TN) of the hair with the following mnemonic:
BLT Noodles
B=Brooms, (e.g. frayed hair fibers with the appearance of two broomsticks pushed together in trichorrhexis nodosa)
L=Low= helps remind you that this is associated with metabolic syndromes, with varying low or high leve … 
On this Mnemonic Monday, we challenge you to remember the side effects of hedgehog inhibitors, vismodegib and sonidegib, with the following mnemonic:
MAD Weight loss
M=muscle spasm (72% of cases)
A=alopecia (64% of cases)
D= dysgeusia (55% of cases)
Weight loss= weight loss (45% of cases)
Click HERE to download or print your mnemonic card.
Study More!
Need a refresher on he … 