On this Mnemonic Monday, we challenge you to remember metabolic syndromes associated with trichorrhexis nodosa (TN) of the hair with the following mnemonic:
B=Brooms, (e.g. frayed hair fibers with the appearance of two broomsticks pushed together in trichorrhexis nodosa)
L=Low= helps remind you that this is associated with metabolic syndromes, with varying low or high levels of minerals/amino acids.
Example: low arginine and low copper in Menkes syndrome, low sulfur in trichothiodystrophy, high citrulline in citrullinemia, low arginine, high ammonia in argininosuccinic aciduria.
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Need a refresher on Trichorrhexis Nodosa (TN)? Check out page 154 of your 2022 Derm In-Review Study Guide.
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Check out the following JDD article on hair disorders including trichorrhexis nodosa:
Human hair has been classified into 3 major groups, as determined by ethnic origin. In these populations, significant structural and biochemical variations of the hair follicle and shaft are seen, as well as unique hair grooming practices. These structural variations of the hair are closely linked to the common disorders of the hair and scalp, such as acquired trichorrhexis nodosa, seborrheic dermatitis, traction alopecia, central centrifugal cicatricial alopecia, dissecting cellulitis, frontal fibrosing alopecia, and pseudofolliculitis barbae.
J Drugs Dermatol. 2013;12(4):420-427.
Read the full article here.
Test your knowledge!
All of the following are associated with trichorrhexis nodosa except:
B. Absent argininosuccinase
C. Netherton syndrome
D. Menkes kinky hair syndrome
E. Bjornstad syndrome
To find out the correct answer and read the explanation, click here.
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