A Massive Case of Cutaneous Diffuse Large B-Cell Lymphoma
B-Cell LymphomaABSTRACT Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, and extranodal involvement is seen in approximately 40% of cases. However, cases involving the skin and muscle are rare, and skin manifestations most commonly present as plaques, papules, small nodules, or ulcers. In this report, JDD authors Lauren E. Merz MD MSc, Christopher B. Hergott MD PhD, and Reb …
B-Cell Lymphoma
JAK Inhibitors in Pediatric Patients | Practical Pearls from the Expert
JAK InhibitorsBe excited about the new medications approved for use in pediatric patients, says Dr. A. Yasmine Kirkorian, chief of dermatology at Children’s National Hospital. Next Steps in Derm, in partnership with ODAC Dermatology, Aesthetic & Surgical Conference, interviewed Dr. Kirkorian about the use of JAK inhibitors in children. Should dermatology clinicians prescribe JAK inhibitors in this patient …
JAK Inhibitors
Patient Buzz: Melanoma Overdiagnosis | The Expert Weighs In
Melanoma OverdiagnosisVerywell Health and several other media outlets are covering the issue of melanoma overdiagnosis in light of a recent study, which estimated more than 80,000 melanomas were overdiagnosed in white Americans in 2018 alone. Is melanoma overdiagnosis among white Americans a significant issue? What are the driving factors of overdiagnosis? What can dermatologists do better when diagnosing melanoma? …
Melanoma Overdiagnosis
Photodamage: Pathogenesis and Clinical Features
PHOTODAMAGENext Steps in Derm, in partnership with Pigmentary Disorders Exchange Symposium interviewed Dr. Susan C. Taylor, Bernett L. Johnson Endowed Professor, director of the Skin of Color Research Fellowship and vice chair for diversity, equity and inclusion in the dermatology department at the Perelman School of Medicine at the University of Pennsylvania. Watch as Dr. Taylor shares the causes of photoda …
PHOTODAMAGE
Spesolimab Therapeutic Cheat Sheet
SpesolimabGeneralized pustular psoriasis (GPP) is a rare, autoinflammatory condition, with acute, severe flares of diffuse sterile pustules and systemic symptoms that can be life-threatening. Historically, cyclosporine, methotrexate, retinoids, and biologics modulating the interleukin-17 (IL-17), IL-23, and tumor necrosis factor α pathways have been used off-label for management.1 Aberrant IL-36 signaling …
Spesolimab