Infantile Rash – Friday Pop Quiz 6/18
The dermatologist on call is requested to visit the NICU to evaluate an infant born 12 hours earlier with a disseminated rash. Two punch biopsies are performed and a c-KIT positive infiltrate is noted in the dermis of each sample. What is the most likely diagnosis?
A. T cell lymphoma
B. Mastocytosis
C. Syphilis, congenital
D. B cell lymphoma
E. Neuroblastoma
To find out the co …
The dermatologist on call is requested to visit the NICU to evaluate an infant born 12 hours earlier with a disseminated rash. Two punch biopsies are performed and a c-KIT positive infiltrate is noted in the dermis of each sample. What is the most likely diagnosis?
A. T cell lymphoma
B. Mastocytosis
C. Syphilis, congenital
D. B cell lymphoma
E. Neuroblastoma
To find out the co … 
On this Mnemonic Monday, we challenge you to remember stains for Mast cells.
"GIMME TO YOUR LEDER"
Giemsa
Toluidine blue
Leder
Remember "rub me and take me to your Leder" as a mnemonic to remember that Leder stain still works after Darier's sign is induced (after de-granulation of mast cells). Side note: Not all stains are included here. Ex: tryptase and c-kit would also stain mast … 
This patient presented for a different lesion but you see this during your exam and perform a biopsy. If the pigmented lesion seen here is 0.9mm deep, what is the recommended margin for excision?
A. <0.5cm
B. 0.5cm
C. 1.0cm
D. 2.0cm
E. >2.0cm
To find out the correct answer and read the explanation, click here.
Brought to you by our brand partner Derm In-Review. A … 
This healthy 2-year-old female presents with a 2-day history of the pruritic rash seen here. She had mild edema of the dorsal hands and feet and positive dermatographism on exam. All lesions were transient, lasting less than 24 hours in the same location. She was otherwise well and her parents denied any fever or systemic symptoms. What is the best diagnosis?
A. Serum sickness-like reaction … 
On this Mnemonic Monday, we challenge you to remember immunohistochemical markers for paget cells in Extramammary Paget’s Disease with the following mnemonic:
"EXTRA GROSS LOVE PASSES CANCER"
Extra- Extramammary Paget’s Disease
Gross- Gross cystic disease fluid protein 15 (GCDFP-15)
LOVE- Low molecular weight cytokeratins
PASses- Period acid-Schiff (PAS)
CANCER- CEA
The wo …