Derm Topics

Patient Buzz Series: How to Use PDRN Products

PDRN is one of the hottest new skincare ingredients, and it’s commonly known from its source – salmon sperm. Products with PDRN are expected to rise in popularity in 2026. Marie Claire posted a primer on PDRN products and how to maximize their benefits. Dermatologist Dr. Deborah Longwill says PDRN products improve hydration and skin barrier repair, and are helpful in the recovery process after resurfacing procedures. PDRN, which stands for polydeoxyribonucleotide, is a DNA fragment, and when extracted from salmon sperm, is noted for its purity and molecular weight. PDRN is used both in at-home products and in-office procedures, such as microneedling with PDRN serums.

USA Today highlighted another unusual skincare ingredient – bee venom. While fans tout anti-microbial and anti-inflammatory effects, dermatologists caution that bee venom by nature has an allergenic potential. Dermatologist Dr. Anthony Rossi says any plumping effect could be a sign of irritation or an allergy, not a cosmetic benefit. Dr. Rossi and other dermatologists quoted in the article recommend patients use skincare products that are backed by research, such as retinol.

Women’s Health looked into the skin effects of hormone therapy during menopause. The FDA recently removed black box warnings from hormone therapy products, which will likely increase interest and access to these medications. In the article, dermatologists outline the skin benefits of estrogen, progesterone, and testosterone as well as the potential negative effects, including melasma, acne breakouts, and increased facial hair. The dermatologists outline ways to combat these negative effects as well as care well for skin changes from menopause.

Finally, Marie Claire looked at the benefits and risks of oral minoxidil for hair growth. While the oral formulation is convenient and effective, dermatologists caution of the side effects, which are more severe than topical minoxidil. Since oral minoxidil lowers blood pressure, dermatologist Dr. Morayo Adisa says it is not for people with heart, liver, or kidney disease, nor is it for those who are pregnant, planning on becoming pregnant, or those who are nursing. In addition, given that oral minoxidil is systemic, patients may experience hair growth in unwanted places, such as the face. Other side effects, such as rapid heartbeat and dizziness, should also be considered, according to dermatologist Dr. Ellen Marmur. 

The consumer skincare world is always buzzing with new trends. Review this list of dermatology news coverage and be in the know:

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