It’s Mnemonic Monday! Extramammary Paget’s Disease
Extramammary Paget’s disease immunohistochemical markersOn this Mnemonic Monday, we challenge you to remember immunohistochemical markers for paget cells in Extramammary Paget’s Disease with the following mnemonic: "EXTRA GROSS LOVE PASSES CANCER" Extra- Extramammary Paget’s Disease Gross- Gross cystic disease fluid protein 15 (GCDFP-15) LOVE- Low molecular weight cytokeratins PASses- Period acid-Schiff (PAS) CANCER- CEA The wo …
Extramammary Paget’s disease immunohistochemical markers
A Spectrum of Skin Tones: An Interview with Drs. Vatanchi & Carrington
A Spectrum of Skin TonesSkin of color is often interpreted simply as “non white” when in fact it should be viewed as a variety of hues on a spectrum. It is important for dermatologists to be equipped with the necessary skills to treat an array of skin tones because one finite mistake can cause unfavorable results depending on the amount of pigment in a patient’s skin. I had the pleasure of interviewing Dr. Marjon V …
A Spectrum of Skin Tones
Coma Bullae – Friday Pop Quiz 5/28
Coma Bullae A 6-month old infant develops tense blisters on the distal extremities which develop on normal-appearing skin. He has a neurologic disease and has been immobilized for a long period of time. The blisters spontaneously heal within 1-2 weeks. You suspect a diagnosis of coma bullae. Which of the following is the key characteristic histologic feature that would assist you in making this diagnosis? …
Coma Bullae
Treatment of Periorificial Dermatitis With Novel Narrow Spectrum Sarecycline
Periorificial DermatitisBroad spectrum tetracyclines are a well-known, widely used, and often successful treatment for use in inflammatory skin pathologies such as acne and rosacea. However, the steady rise of antibiotic resistance and gut dysbiosis associated with broad spectrum tetracyclines emphasizes the importance and responsibility of antibiotic stewardship. Narrow spectrum antibiotics have become increasingly impo …
Periorificial Dermatitis
Calciphylaxis – Friday Pop Quiz 5/21
A 65-year-old female patient presents with poorly demarcated, symmetric, very painful patches of erythema and retiform purpura, favoring the thighs and buttocks. Bullae and a dusky gray discoloration developed, as well as the appearance of ulcerations with black, leathery eschars. A skin biopsy of the affected area is suggestive of calciphylaxis. Shortly after, she dies from secondary infectio …