Hand Foot Skin Reaction Associated With Palbociclib
PalbociclibINTRODUCTION Palbociclib is one of three new small-molecule inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) approved for use in the treatment of hormone receptor positive (HR+) and human epidermal growth factor receptor 2 negative (Her2-) advanced or metastatic breast cancer. CDK4/6 inhibitors have a good overall safety profile but reported side effects include cytopenias, diarrhea, QTc pr …
Palbociclib
A Spectrum of Skin Tones: An Interview with Drs. Vatanchi & Carrington
A Spectrum of Skin TonesSkin of color is often interpreted simply as “non white” when in fact it should be viewed as a variety of hues on a spectrum. It is important for dermatologists to be equipped with the necessary skills to treat an array of skin tones because one finite mistake can cause unfavorable results depending on the amount of pigment in a patient’s skin. I had the pleasure of interviewing Dr. Marjon V …
A Spectrum of Skin Tones
Treatment of Periorificial Dermatitis With Novel Narrow Spectrum Sarecycline
Periorificial DermatitisBroad spectrum tetracyclines are a well-known, widely used, and often successful treatment for use in inflammatory skin pathologies such as acne and rosacea. However, the steady rise of antibiotic resistance and gut dysbiosis associated with broad spectrum tetracyclines emphasizes the importance and responsibility of antibiotic stewardship. Narrow spectrum antibiotics have become increasingly impo …
Periorificial Dermatitis
Lichen Planopilaris and Frontal Fibrosing Alopecia: Treatment Algorithms
lichen planopilaris and frontal fibrosing alopeciaDr. Jerry Shapiro, or the “Lord of the Hair” (as described by ODAC conference co-chair Dr. Adam Friedman) provided us with an A to Z overview of frontal fibrosing alopecia (FFA) and lichen planopilaris (LPP) as well royalty-worthy pearls and treatment updates. Before we start, here are my favorite quotes from Dr. Shapiro, which also serve as a great summary of his wonderful lecture: “Fro …
lichen planopilaris and frontal fibrosing alopecia
Recalcitrant Dyshidrotic Eczema Treated With Dupilumab
eczemaThe following two cases presented by JDD authors Ryan A. Gall MD, John D. Peters MD, and Alyson J. Brinker MD add to the growing literature supporting the use of dupilumab in the treatment of patients with recalcitrant dyshidrotic eczema, both with and without diagnosed contact allergens. Introduction Dyshidrotic eczema, also known as dyshidrosis or pompholyx when involving larger bullae, is a c …
eczema
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