Friday Pop Quiz #25
Answer: D: Oral therapy for this disease targets smoothened.
This image shows a classic rodent ulcer of basal cell carcinoma (BCC). The overall risk of metastasis in all BCCs is quite low, 0.028-0.55%. However, large, ulcerated BCCs have a higher risk of metastasis. The risk of metastasis is 1.9% for BCCs greater than 3.0 cm and up to 45.0% for BCCs greater than 10 cm.
Two hedgehog pathway inh …