Hydroxychloroquine, Pentoxifylline, and Colchicine: Off-Label is ON in Dermatology
So many diseases, so few FDA approved indications. Between the mind-numbing time and cost from bench to bottle, it is no surprise that dermatologists, as masters of the integument are the off-label bandits, marrying their wealth of knowledge on the pathophysiology of skin diseases to the mechanisms by which medications work to create an evidenced-based armament of therapies for both common and rar …
So many diseases, so few FDA approved indications. Between the mind-numbing time and cost from bench to bottle, it is no surprise that dermatologists, as masters of the integument are the off-label bandits, marrying their wealth of knowledge on the pathophysiology of skin diseases to the mechanisms by which medications work to create an evidenced-based armament of therapies for both common and rar … 
Hormonal acne is a prevalent and frustrating condition among many women. For those who are unable to control the disease with topical medications alone, spironolactone is often a useful systemic agent. However, its off-label use and potential risk of hyperkalemia have raised the question about serum potassium monitoring. We continue our Therapeutic Cheat Sheet series, with a closer look at spirono … 
In this case series, JDD authors evaluate the efficacy and safety of intralesional triamcinolone acetonide injections (ILK) when used with topical minoxidil in the management of traction alopecia in 6 African American women.
Background
Traction alopecia (TA) is a form of hair loss secondary to repetitive and/or prolonged tension to a hair follicle over an extended period of time. This typically … 
In part 1 of this 2-part series, Dr. Kircik along with JDD authors Vlatka Agnetta MD, Abel Torres MD JD MBA, Seemal R. Desai MD, and Adelaide A. Hebert MD, reviewed the regulatory landscape of compounding in dermatology, including federal and state regulations. In part 2, they discuss FDA and USP Compounding Lists/ Categories and provide their final thoughts on in-office compounding.
FDA Compound … 
Next Steps in Derm, in partnership with ODAC Dermatology, Aesthetic and Surgical Conference, is excited to share a new video series where dermatology key opinion leaders share important updates and pearls on a variety of medical, surgical, and aesthetic dermatology topics.
First up is Dr. Amy McMichael, Professor and Chair of Dermatology at the Wake Forest University School of Medicine, sharing … 