Cicatricial Alopecias: Practical Pearls for Challenging Diagnoses
cicatricial alopeciasAt ODAC 2023, we had the opportunity to learn about cicatricial alopecias from renowned dermatologist and hair expert Dr. Amy McMichael, Professor of Dermatology at Wake Forest University School of Medicine. First, we considered a framework to check for cicatricial alopecias. This is particularly important because if we can identify cicatricial alopecia, we can make sure we are treating the rig …
cicatricial alopecias
Friday Pop Quiz #246
The correct answer is C. Interleukin-13. IL-13 is an important T-helper cell 2 cytokine involved in acute inflammation of atopic dermatitis. While interferon-gamma, interleukin-2, transforming growth factor-beta, and tumor necrosis factor-alpha may be involved in an inflammatory response, they are not most implicated in acute inflammation of atopic dermatitis. References: Wollenb …
Topical Ruxolitinib Therapeutic Cheat Sheet
RuxolitinibRuxolitinib (OPZELURA) is a twice daily topical cream that is FDA approved for non-segmental vitiligo and mild to moderate atopic dermatitis1. JAK inhibitors are a class of drugs effective in treating a wide variety of inflammatory conditions. Initially only FDA approved for non-dermatologic conditions such as rheumatoid arthritis and ulcerative colitis, there is now strong evidence that JAK/STAT …
Ruxolitinib
Skin Papule – Friday Pop Quiz 11/10/2023
A 32-year-old female presents with a firm, minimally elevated papule that measures 5 mm in diameter and is hyper pigmented. On palpation, the lesion seems attached to subcutaneous tissue. On dermoscopy, a central white scar-like patch surrounded by a delicate pigment network is observed. Which of the following has not been found to be associated with multiple dermatofibromas? A. HIV infecti …
Friday Pop Quiz #245
The correct answer is E. Melanocytic nevi. Melanocytic nevi is not a common cause of multiple dermatofibromas. Although some dermatofibromas are thought to arise at sites of trauma or arthropod bites, their precise etiology is not known. Multiple eruptive dermatofibromas have been observed in patients with autoimmune disorders such as lupus erythematosus and atopic dermatitis and in the …
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