Friday Pop Quiz 3/13/2026
A 75-year-old man presents with tense bullae as pictured. DIF reveals linear IgG and C3 at the dermal-epidermal junction. On salt-split skin, immunoreactants are localized to the roof of the specimen. What is the target antigen?
A. Type VII Collagen
B. Type XVII collagen (BP180)
C. Laminin 332
D. Desmoglein 1
E. Integrin α6β4
To find out the correct answer and read the expl …
A 75-year-old man presents with tense bullae as pictured. DIF reveals linear IgG and C3 at the dermal-epidermal junction. On salt-split skin, immunoreactants are localized to the roof of the specimen. What is the target antigen?
A. Type VII Collagen
B. Type XVII collagen (BP180)
C. Laminin 332
D. Desmoglein 1
E. Integrin α6β4
To find out the correct answer and read the expl … 
A 70-year-old woman with biopsy-confirmed bullous pemphigoid presents with new-onset confusion, hypotension, and leukocytosis two weeks after starting systemic prednisone 60 mg daily. She also reports tremors and blood glucose of 320 mg/dL. What is the next best step in management?
A. Taper corticosteroids and begin doxycycline and … 
Introducing the April 2024 Editorial Highlights from the Journal of Drugs in Dermatology! This month's issue is packed with groundbreaking research and insights into dermatologic treatments and practices. From original articles exploring innovative therapies for conditions like photoaging and acne vulgaris to case reports shedding light on rare dermatologic phenomena, this issue offers a comprehen … 
Intravenous immune globulin (IVIG) is a concentrate of pooled immunoglobulins derived from plasma donors. Its unique mechanism of action expands the utility of the medication to a variety of conditions. We continue our series, Therapeutic Cheat Sheet, with a closer look at IVIG, which is FDA-approved for the treatment of dermatologic conditions including dermatomyositis, Kawasaki disease, ITP, and … 
At ODAC 2023, we had the opportunity to learn about the latest in treatments for blistering diseases from Dr. Karl Saardi, Associate Professor and Director of Inpatient Dermatology at George Washington University. We focused on the pemphigus and pemphigoid group of diseases, which we will review and summarize here.
Pemphigus
The pemphigus group of diseases is characterized by intraepidermal auto …