hypopigmentation

Refractory Alopecia Areata and Vitiligo Responding to Tofacitinib Monotherapy
Tofacitinib
by NEXT STEPS IN DERM TEAM on
INTRODUCTION Tofacitinib is a Janus kinase (JAK) 1-3 inhibitor first U.S. Food and Drug Administration (FDA) approved in 2012 for rheumatoid arthritis, with subsequent approval for psoriatic arthritis, ulcerative colitis, polyarticular course juvenile idiopathic arthritis, and ankylosing spondylitis in 2017, 2018, 2020, and 2021, respectively.1,2 In the last several years, oral tofacitinib …
Hydroquinone Therapeutic Cheat Sheet
hydroquinone
by Kamaria Nelson, MD on
Hydroquinone is the most commonly used depigmentation agent and is a first-line treatment for melasma.1Hydroquinone was available previously in over-the-counter products and is currently available in prescription formulations with common concentration ranges of 0.4 to 5%. Prescription strengths available in the United States include hydroquinone 2% and 4% cream and hydroquinone 2% gel.2,3 In Septe …
Disorders of Pigmentation: Diagnostic Considerations
disorders of pigmentation
by Cula N. Dautriche, MD, PhD on
Pigmentation is key to photoprotection of the skin, eye color, and enhanced barrier function. With increased pigmentation, photoaging is minimized with a concurrent decrease in frequency of skin cancer. In skin of color, these pigmentary advantages come at a cost. These include an increased risk of hyperpigmentation and/or hypopigmentation, hypertrophic scars, keloids, scarring alopecia, and vitam …
Isotretinoin in Acne: Fact vs Fiction
Isotretinoin
by Jacqueline McKesey, MD, MS on
Dr. Lester is the Director of the Skin of Color Program at the Department of Dermatology University of California San Francisco. Wow! This means we got a “two for one special” from her lecture, not only learning about the truths and myths associated with the use of isotretinoin in acne but also recognizing that those who are underrepresented minorities or socioeconomically disadvantaged may no …
What’s New on the Vitiligo Treatment Horizon
New Vitiligo Treatments
by NEXT STEPS IN DERM TEAM on
Next Steps in Derm, in partnership with ODAC Dermatology, Aesthetic and Surgical Conference, interviewed Dr. John Harris, Vice-Chair of Dermatology and Director of the Vitiligo Clinic and Research Center at UMass Medical School in Worcester, Massachusetts, on new vitiligo treatments in the horizon. Watch as he shares recent discoveries that have influenced the way that we diagnose and manage pat …