Topical Ketoconazole Therapeutic Cheat Sheet
Ketoconazole is an imidazole antifungal that was initially FDA-approved in an oral formulation for the treatment of systemic fungal infections. While oral ketoconazole has largely fallen out of use due to safety concerns, including hepatotoxicity, endocrine dysregulation, and drug interactions, topical ketoconazole has proven to be a safe and effective treatment for superficial fungal infections. …
Ketoconazole is an imidazole antifungal that was initially FDA-approved in an oral formulation for the treatment of systemic fungal infections. While oral ketoconazole has largely fallen out of use due to safety concerns, including hepatotoxicity, endocrine dysregulation, and drug interactions, topical ketoconazole has proven to be a safe and effective treatment for superficial fungal infections. … Continue reading "Topical Ketoconazole Therapeutic Cheat Sheet"
Ciclopirox is the only hydroxypyridone antifungal agent with a unique mechanism of action differentiating it from other antimycotic agents. Unlike the azole-antifungals which block the sterol synthesis in the fungal cell membrane, ciclopirox functions by chelating cations resulting in the degradation of fungal cells, as well as proposed anti-inflammatory properties. It is available in a variety of … 
JDD authors Dimitra Xenopoulou MS, Christopher Pochat MS, and Evelyn Greco DO present the findings of a successful treatment for verrucous psoriasis.
CASE
A 64-year-old female presented to the outpatient clinic for the evaluation of flaking and itchy lesions on her bilateral hands and feet that were present for several months and caused difficulty with activities of daily living. Inconsist … 
A 92-year-old female patient presents with complaints regarding her nails. She states they often crumble, and have been yellowish in color for years. Her toenails are so thickened that it is difficult to trim them. She is otherwise asymptomatic and has no fingernail involvement. What is the most common cause of this patient's condition?
A. Tinea manuum
B. Tinea pedis
C. Inflammatory d … 
Dermatophyte infections are estimated to affect about 25% of the world’s population, representing some of the most common infections in the world. Conditions such as onychomycosis and tinea capitis may significantly impact quality of life by way of their symptoms or appearance, making adequate treatment important. Oral and topical formulations of terbinafine are commonly used on- and off-label f … 