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Novel Association of Retinol Myrtus Extract Complex Mediated Elastin and Collagen Expression With Epigenetic Changes Through miRNAs Regulators

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Background

  • A facial moisturizer incorporating the extract of Myrtus communis and retinol (ROL) was developed, and studies previously showed that this retinol Myrtus extract complex enhancing ROL activity helped to clinically delay and reduce the signs of skin aging
  • Retinol Myrtus extract complex was previously shown to exert its many skin benefits through transcriptional activation
  • Recent studies suggest epigenetic regulation through micro RNAs (miRNAs), specific inhibitors of targeted gene translation, may also play a role in the regulation of skin aging
  • The objective of this study was to investigate whether the rejuvenating skin benefits of retinol Myrtus extract complex could also be associated with epigenetic regulation of miRNAs in human skin

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Conclusions