Severe Oral Mucositis: A Rare Adverse Event of Pembrolizumab
Treatment of malignancy with anti-programmed cell death 1 (PD-1) immune checkpoint inhibitors can cause mucocutaneous side effects resulting from T cell activation. Due to their recent development, the full side effect profile remains to be fully elucidated, however dermatologic adverse events are most common. The main oral toxicities of these immune checkpoint inhibitors include: xerostomia, dysg …
Treatment of malignancy with anti-programmed cell death 1 (PD-1) immune checkpoint inhibitors can cause mucocutaneous side effects resulting from T cell activation. Due to their recent development, the full side effect profile remains to be fully elucidated, however dermatologic adverse events are most common. The main oral toxicities of these immune checkpoint inhibitors include: xerostomia, dysg … Continue reading "Severe Oral Mucositis: A Rare Adverse Event of Pembrolizumab"
I believe one of the most valuable aspects of attending conferences such as ODAC is to “fill in the gaps” in important topics that are often missing in our regular dermatology training. While US dermatology residency programs provide the foundation for providing the highest level of dermatologic care to our patients, they are often lacking in teaching the business side of medicine and practica …
Atopic dermatitis (AD) is a common skin condition characterized by pruritus and occurs as a result of factors related to impaired skin barrier and immune response, as well as environmental and infectious agents. Patients with poor control on topical therapy are looking for safe and effective systemic treatments. We continue our series, Therapeutic Cheat Sheet, with a closer look at dupilumab, whic …
To kick off ODAC 2021, Dr. Yasmine Kirkorian, MD, tackled two clinical dilemmas that are frequently seen among pediatric patients in the dermatology office: poorly controlled atopic dermatitis and infantile hemangiomas. Dr. Kirkorian reviewed currently available systemic therapies for atopic dermatitis as well those in the drug development pipeline. She went into detail about how she utilizes he …
This month’s Patient Buzz includes articles discussing a variety of topics such as itchy, raised tattoos (is this normal?), blue light protection skincare, and other topics uniquely related to the COVID-19 pandemic. Is COVID-19 to blame for eczema flares? Is makeup gone unused in the pandemic still safe to use? Is blue light from extra screen time during the pandemic damaging our skin? What are …