Pyoderma Gangrenosum Following Total Colectomy for Ulcerative Colitis
Introduction
Pyoderma gangrenosum (PG) is a rare, neutrophilic dermatosis characterized by rapidly enlarging, painful ulcers with violaceous and undermined borders. It is commonly associated with systemic disorders, including rheumatoid arthritis, hematologic malignancies, and inflammatory bowel disease (IBD).¹ While PG often correlates with IBD flares, its pathogenesis is not well understood. C …
Introduction
Pyoderma gangrenosum (PG) is a rare, neutrophilic dermatosis characterized by rapidly enlarging, painful ulcers with violaceous and undermined borders. It is commonly associated with systemic disorders, including rheumatoid arthritis, hematologic malignancies, and inflammatory bowel disease (IBD).¹ While PG often correlates with IBD flares, its pathogenesis is not well understood. C … Continue reading "Pyoderma Gangrenosum Following Total Colectomy for Ulcerative Colitis"
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Introduction
Benign Familial Pemphigus (Hailey-Hailey Disease [HHD]) is caused by a mutation within ATP2C1, the gene encoding the calcium pump of golgi apparatuses, impacting keratinocytes' ability to adhere to each other, resulting in acantholysis.1 Clinical presentation of HHD encompasses blisters that become erythematous plaques and fissures within flexural areas on a relapsing basis …