Botulinum Toxin in the Long-Term Treatment of Refractory Raynaud’s Phenomenon
Raynaud’s phenomenon is an exaggerated physiological response of blood vessels in the distal extremities to emotional stress and cold. It can be idiopathic or secondary to a connective tissue disorder, such as scleroderma or systemic lupus erythematosus. Treatment for Raynaud’s phenomenon consists primarily of lifestyle modifications; if unsuccessful, pharmacotherapy with dihydropyridine calci …
Raynaud’s phenomenon is an exaggerated physiological response of blood vessels in the distal extremities to emotional stress and cold. It can be idiopathic or secondary to a connective tissue disorder, such as scleroderma or systemic lupus erythematosus. Treatment for Raynaud’s phenomenon consists primarily of lifestyle modifications; if unsuccessful, pharmacotherapy with dihydropyridine calci … Continue reading "Botulinum Toxin in the Long-Term Treatment of Refractory Raynaud’s Phenomenon"
Facial fillers are an increasingly popular cosmetic procedure used for facial rejuvenation. Regardless of the experience and skill level of the injector, fillers can inadvertently occlude vessels leading to blockage of cutaneous blood supply, ischemic skin necrosis and rarely cerebrovascular strokes and blindness. Injectors should recognize early signs of occlusion and be prepared with knowledge a … 
Palmoplantar pustulosis (PPP) is a rare, recurrent skin disorder that presents a major challenge to clinical therapy. JDD author Danilo C. Del Campo, MD, FAAD reports a case of a 69-year-old woman with a 20-year history of psoriasis with skin manifestations and clinical and pathologic features consistent with PPP. After intolerance to apremilast and unsuccessful use of topical corticosteroids and … 
Pyoderma Gangrenosum Occurring in the Setting of Hypercortisolism Associated With Adrenocortical Adenoma: A Pathophysiological Paradox
Pyoderma gangrenosum (PG) is a challenging, rare, ulcerating skin disease characterized by neutrophilic abundance and absence of infection, often associated with systemic diseases. JDD authors Chapman Wei, Elizabeth Hazuka, Peter DeRosa, Jill M. Paulson MD, and Ad … 
Authors Adam J. Friedman MD, Kimia Momeni BS, and Mikhail Kogan MD present a case of a young man with psoriasis managed with topical cannabinoids.
Introduction
The interest in use of medical cannabis for chronic dermatologic conditions such as psoriasis, eczema, and acne has been growing mostly owing to rapidly emerging decriminalization across the country and impressive commercially driven popu …