On this Mnemonic Monday, we challenge you to remember findings/mutations associated with Familial LPL deficiency (type I hyperlipoproteinemia) with the following mnemonic:
AudRey got lipo for her 1st Cat because he had low self-esteem from being blind and having no abs.
Au(d)Re(y)- Autosomal recessive
Lipo– Lipoprotein lipase deficiency
C(at)- Apolipoprotein C-II
(because he had low self-esteem from being)
Blind– lipemia retinalis (opaque yellow retinal vessels)
(and having no)
Ab(s)- abdominal pain/pancreatitis/hepatomegaly
This mnemonic refers to findings/mutations associated with familial hypercholesterolemia/Apo-B deficiency (Type II). This is an Autosomal dominant mutation of LDL receptor or Apo B-100 mutation. It is the most common hyperlipoproteinemia (1:500 heterozygous). Clinically we see tendinous, tuberoeruptive, tuberous, or plane xanthomas (remember plane xanthomas of finger webs are pathognomonic for homozygous Apo B-100 mutation), as well as xanthelasma and atherosclerosis.
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Test your knowledge!
Increased chylomicrons are a feature of which type of hyperlipoproteinemia?
A. Type I
B. Type IIa
C. Type IIb
D. Type III
E. Type IV
To find out the correct answer and read the explanation, click here.
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