Treatment of Periorificial Dermatitis With Novel Narrow Spectrum Sarecycline
Broad spectrum tetracyclines are a well-known, widely used, and often successful treatment for use in inflammatory skin pathologies such as acne and rosacea. However, the steady rise of antibiotic resistance and gut dysbiosis associated with broad spectrum tetracyclines emphasizes the importance and responsibility of antibiotic stewardship. Narrow spectrum antibiotics have become increasingly impo …
Broad spectrum tetracyclines are a well-known, widely used, and often successful treatment for use in inflammatory skin pathologies such as acne and rosacea. However, the steady rise of antibiotic resistance and gut dysbiosis associated with broad spectrum tetracyclines emphasizes the importance and responsibility of antibiotic stewardship. Narrow spectrum antibiotics have become increasingly impo … Continue reading "Treatment of Periorificial Dermatitis With Novel Narrow Spectrum Sarecycline"
Case Scenario
A 26-year-old patient presents to the dermatology clinic with severe nodulocystic scarring acne. The patient identifies as a transgender male and notes that he has been receiving hormone replacement therapy for the past 4 years with weekly intramuscular testosterone injections. He has not had any gender-affirming surgeries and reports being currently amenorrhoeic. He is curren … 
The following two cases presented by JDD authors Ryan A. Gall MD, John D. Peters MD, and Alyson J. Brinker MD add to the growing literature supporting the use of dupilumab in the treatment of patients with recalcitrant dyshidrotic eczema, both with and without diagnosed contact allergens.
Introduction
Dyshidrotic eczema, also known as dyshidrosis or pompholyx when involving larger bullae, is a c … 
Atopic dermatitis (AD) is a chronic inflammatory skin disease. The pathogenesis of AD is complex with many mediators involved and can be broken down into 4 categories:
Immune dysregulation
Abnormal skin barrier
Abnormal itch/scratch cycle
Abnormal skin microbiome
In AD, there is a breakdown in molecular control of the immune system, leading to overproduction and expressi … 
Dr. Hanke, a dermatologic surgeon who needs no introduction (but I’ll give one anyway!) provided us with an evidence-based discussion of field treatments available for actinic keratoses at ODAC 2021 conference.
Just to name a few of Dr. Hanke’s accomplishments, he is the current Senior Vice President of the Skin Cancer Foundation, Senior editor of JDD, and the former president of the AAD, A … 