depigmentation

Multiple Halo Nevi Induced by Intense Sun Exposure
Halo NeviJDD authors  present the case of a 38-year-old male who reported to their practice with multiple newly developed halos around 26 existing nevi on his trunk. The halo nevi developed after the patient, who lived in the northeast, spent 2 months on a lake in Alabama, with intense heat and sun exposure. This case is remarkable in that it points to ultraviolet exposure as one instigating factor in the …
Halo Nevi
Disorders of Depigmentation: Focus on Vitiligo
vitiligoAt the 2023 ODAC Dermatology, Aesthetic & Surgical Conference, we were lucky to learn about the management of vitiligo from the renowned researcher and clinician, Dr.  John Harris, Professor and Chair of Dermatology at the University of Massachusetts. When a new patient with vitiligo presents to my clinic, I always pull out my phone to consult Dr. Harris’ treatment protocol – I am sure I …
vitiligo
Refractory Alopecia Areata and Vitiligo Responding to Tofacitinib Monotherapy
Tofacitinib INTRODUCTION Tofacitinib is a Janus kinase (JAK) 1-3 inhibitor first U.S. Food and Drug Administration (FDA) approved in 2012 for rheumatoid arthritis, with subsequent approval for psoriatic arthritis, ulcerative colitis, polyarticular course juvenile idiopathic arthritis, and ankylosing spondylitis in 2017, 2018, 2020, and 2021, respectively.1,2 In the last several years, oral tofacitinib …
Tofacitinib
Hydroquinone Therapeutic Cheat Sheet
hydroquinoneHydroquinone is the most commonly used depigmentation agent and is a first-line treatment for melasma.1Hydroquinone was available previously in over-the-counter products and is currently available in prescription formulations with common concentration ranges of 0.4 to 5%. Prescription strengths available in the United States include hydroquinone 2% and 4% cream and hydroquinone 2% gel.2,3 In Septe …
hydroquinone
Current and Emerging Management Strategies for Vitiligo
vitiligoVitiligo is an autoimmune skin disease that affects >3 million individuals in the US and around 74 million worldwide. In addition to physical symptoms such as itch, it can be particularly cosmetically concerning and psychologically distressing. It mainly affects young individuals, where it is estimated that 50% of cases have onset before the age of 20. Importantly, it is associated with other a …
vitiligo