dermatopathology

It’s Mnemonic Monday! Neurofibromatosis Major Diagnostic Criteria
NeurofibromatosisOn this Mnemonic Monday, we challenge you to remember the major diagnostic criteria for neurofibromatosis type I with the following mnemonic: Chase Bank LOANS C- Café-au-lait spots B- Bony abnormalities (sphenoid wing dysplasia, pseudoarthrosis, sphenoid dysplasia, scoliosis) L- Lisch nodules (iris hamartomas) O-Optic glioma A- Axillary/inguinal freckling (Crowe’s sign …
Neurofibromatosis
It’s Mnemonic Monday! Stains for Mast Cells
stains for mast cellsOn this Mnemonic Monday, we challenge you to remember stains for Mast cells. "GIMME TO YOUR LEDER" Giemsa Toluidine blue Leder Remember  "rub me and take me to your Leder" as a mnemonic to remember that Leder stain still works after Darier's sign is induced (after de-granulation of mast cells). Side note: Not all stains are included here. Ex: tryptase and c-kit would also stain mast …
stains for mast cells
It’s Mnemonic Monday! Extramammary Paget’s Disease
Extramammary Paget’s disease immunohistochemical markersOn this Mnemonic Monday, we challenge you to remember immunohistochemical markers for paget cells in Extramammary Paget’s Disease with the following mnemonic: "EXTRA GROSS LOVE PASSES CANCER" Extra- Extramammary Paget’s Disease Gross- Gross cystic disease fluid protein 15 (GCDFP-15) LOVE- Low molecular weight cytokeratins PASses- Period acid-Schiff (PAS) CANCER- CEA The wo …
Extramammary Paget’s disease immunohistochemical markers
It’s Mnemonic Monday! Subepidermal and pauci-inflammatory disorders
Subepidermal and pauci-inflammatory disorders in dermatopathologyOn this Mnemonic Monday, we challenge you to remember the list of subepidermal and pauci-inflammatory disorders in dermatopathology: Porphyria cutanea tarda (PCT) Epidermolysis bullousa acquisita (EBA) Toxic epidermal necrolysis/Stevens-Johnson syndrome (TEN/SJS) Bullous pemphigoid Cicatricial pemphigoid Dermatitis herpetiformis Bullous lupus erythematosus (think “SLE”) Linear IgA bu …
Subepidermal and pauci-inflammatory disorders in dermatopathology
Reactive Dermal Infiltrates – Friday Pop Quiz 01/29
A pregnant 33-year-old female presents with the shown painful lesions that appeared abruptly one week ago. She additionally has been febrile to 38.3C with malaise and headaches. What do you expect to find on biopsy of a representative lesion? A. Perivascular neutrophils with fibrinoid necrosis and RBC extravasation B. Apoptotic individual keratinocytes with intracellular spongiosis …