Hydroxychloroquine, Pentoxifylline, and Colchicine: Off-Label is ON in Dermatology
So many diseases, so few FDA approved indications. Between the mind-numbing time and cost from bench to bottle, it is no surprise that dermatologists, as masters of the integument are the off-label bandits, marrying their wealth of knowledge on the pathophysiology of skin diseases to the mechanisms by which medications work to create an evidenced-based armament of therapies for both common and rar …
So many diseases, so few FDA approved indications. Between the mind-numbing time and cost from bench to bottle, it is no surprise that dermatologists, as masters of the integument are the off-label bandits, marrying their wealth of knowledge on the pathophysiology of skin diseases to the mechanisms by which medications work to create an evidenced-based armament of therapies for both common and rar … 
Unfortunately for many residency graduates, a lot of the decisions regarding interactions with industry such as pharmaceutical and medical device sales forces have been made into policies. These are often parallel to the strictures of parents attempting to shelter their children from what is socially perceived as “evil” or “influential,” and in many instances has led to the development … 