off-label dermatology drugs

Thalidomide for Dermatologic Conditions | Therapeutic Cheat Sheet
ThalidomideThalidomide was introduced in the 1950s as a “safe” sleeping medication; however, it quickly became vilified and was removed from the market for its severe teratogenic effects, most commonly phecomelia, or loss of arms and legs. Despite these devastating birth defects, thalidomide has a variety of indications for dermatologic conditions, with manageable side effects when used appropriately. We …
Thalidomide
Oral Glycopyrrolate for Hyperhidrosis | Therapeutic Cheat Sheet
Glycopyrrolate for hyperhidrosisHyperhidrosis affects up to 4.8% of people in the United States, causing significant impacts in patient quality of life.1 Often times, the etiology of symptoms cannot be identified, resulting in a subset of disease termed “primary hyperhidrosis.” Symptoms may be focal or generalized. Because there is a scarcity of FDA-approved treatments for primary hyperhidrosis, treatment often requires a mu …
Glycopyrrolate for hyperhidrosis
Pregabalin for Chronic Pruritus | Therapeutic Cheat Sheet
Chronic pruritus affects 8-16% of the general population and has a profound impact on patient quality of life.1-3Although the symptom of pruritus may originate from a number of underlying etiologies, including metabolic derangements and infectious causes, along with neoplastic, inflammatory, or psychiatric conditions, other cases may be idiopathic in nature.4 Given the diversity of underlying cont …