Calling All Derms! Chronic Spontaneous Urticaria Is For You!
At the 2024 ODAC Dermatology, Aesthetic & Surgical Conference, we were lucky to learn about the management of chronic spontaneous urticaria (CSU) from the renowned researcher and clinician, Dr. Adam J. Friedman, Professor and Chair of Dermatology at The George Washington University School of Medicine and Health Sciences. CSU can be a frustrating, exhausting condition for patients to endure, wi …
At the 2024 ODAC Dermatology, Aesthetic & Surgical Conference, we were lucky to learn about the management of chronic spontaneous urticaria (CSU) from the renowned researcher and clinician, Dr. Adam J. Friedman, Professor and Chair of Dermatology at The George Washington University School of Medicine and Health Sciences. CSU can be a frustrating, exhausting condition for patients to endure, wi … Continue reading "Calling All Derms! Chronic Spontaneous Urticaria Is For You!"
INTRODUCTION
Benign Familial Pemphigus, or Hailey-Hailey Disease (HHD), affects intertriginous areas of the skin causing epidermal blistering and vesicles that coalesce into weeping and crusting plaques.¹
The loss-of-function mutation of the ATP2C1 gene causes a disruption in calcium homeostasis of keratinocytes. The resulting dysfunction in desmosomes and cell-cell adhesion causes acanthol … 
A patient comes in with the rash pictured below consisting of pustules in an annular or polycyclic configuration. What type of paraproteinemia can this disorder be associated with and thus a workup should be initiated for?
A. IgG kappa
B. IgG lambda
C. IgA
D. IgM
E. IgD
To find out the correct answer and read the explanation, click here.
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A 14-year-old female presents with the sudden onset of the skin findings pictured diffusely covering greater than 90% of her skin surface. The rash is accompanied by a high fever (40C) and elevated white blood cell count. What is the most likely cause of her condition?
A. ABCC6 mutation
B. Anti-FceR1 IgG antibodies
C. Anti-transglutaminase 3 antibodies
D. Deficiency of the IL-36 re … 
A 23-year-old female presents with itchy and irritated rash in the image. The rash began in her late teens. She has a family history of similar rash in her mother. Which histocompatibility antigen is most likely in this patient?
A. HLA-Cw2
B. HLA-Cw6
C. HLA-B51
D. HLA-B27
E. HLA-Bw35
To find out the correct answer and read the explanation, click here.
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