ANSWER: IgA Monoclonal Gammopathies Test Question

The correct answer is E. Pyoderma gangrenosusm

Correct Answer Explanation

Pyoderma gangrenosum is an destructive, inflammatory disease of the skin characterized by a painful nodule or pustule that later forms a progressively enlarging ulcer. On pathology, there is a neutrophilic infiltrate with leukocytoclasia. Diseases that have been associated with pyoderma gangrenosum include inflammatory bowel disease, arthritis, an IgA monoclonal gammopathy (primarily), and myelodysplasia.

Incorrect Answer Explanation

The other listed conditions are not associated with IgA gammopathy.

References

Wollina et al. Pyoderma gangrenosum – a review. Orphanet Journal of Rare Diseases2007. https://ojrd.biomedcentral.com/articles/10.1186/1750-1172-2-19