The correct answer is B. 1 month.
Isotretinoin is a synthetic retinoid that is used primarily in the treatment of acne. Isotretinoin has a half-life of approximately 20 hours. Women should be advised to avoid becoming pregnant for at least one month.
The other listed time frames are not correct.
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835909/
