Hand Foot Skin Reaction Associated With Palbociclib
INTRODUCTION
Palbociclib is one of three new small-molecule inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) approved for use in the treatment of hormone receptor positive (HR+) and human epidermal growth factor receptor 2 negative (Her2-) advanced or metastatic breast cancer. CDK4/6 inhibitors have a good overall safety profile but reported side effects include cytopenias, diarrhea, QTc pr …
INTRODUCTION
Palbociclib is one of three new small-molecule inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) approved for use in the treatment of hormone receptor positive (HR+) and human epidermal growth factor receptor 2 negative (Her2-) advanced or metastatic breast cancer. CDK4/6 inhibitors have a good overall safety profile but reported side effects include cytopenias, diarrhea, QTc pr … Continue reading "Hand Foot Skin Reaction Associated With Palbociclib"
Chronic pruritus affects 8-16% of the general population and has a profound impact on patient quality of life.1-3Although the symptom of pruritus may originate from a number of underlying etiologies, including metabolic derangements and infectious causes, along with neoplastic, inflammatory, or psychiatric conditions, other cases may be idiopathic in nature.4 Given the diversity of underlying cont …
Media-savvy dermatologists, reporters and editors who cover the specialty share insightful tips on navigating media relations in dermatology.
Talk to any media savvy dermatologist and you’ll hear stories of interview successes – coverage that was fair and accurate – as well as interview disappointments.
“You say something, they take a snippet and it’s put in not exactly the way you …
On this Mnemonic Monday, we challenge you to remember stains for Mast cells.
"GIMME TO YOUR LEDER"
Giemsa
Toluidine blue
Leder
Remember "rub me and take me to your Leder" as a mnemonic to remember that Leder stain still works after Darier's sign is induced (after de-granulation of mast cells). Side note: Not all stains are included here. Ex: tryptase and c-kit would also stain mast …
On this Suncare Sunday: Sunburn Facts, we share newly published data from the CDC showing sunburn incidence in adults and teens, sun exposure behaviors and sun protection basics:
Sunburn incidence in adults remains high:
34% of adults report experiencing at least 1 sunburn each year1
Half were outside for more than 1 hour between 10 and 4 pm2
Only 5% reported they were tryin …