Recalcitrant Dyshidrotic Eczema Treated With Dupilumab
eczemaThe following two cases presented by JDD authors Ryan A. Gall MD, John D. Peters MD, and Alyson J. Brinker MD add to the growing literature supporting the use of dupilumab in the treatment of patients with recalcitrant dyshidrotic eczema, both with and without diagnosed contact allergens. Introduction Dyshidrotic eczema, also known as dyshidrosis or pompholyx when involving larger bullae, is a c …
eczema
Tranexamic Acid to Prevent and Treat Post-Inflammatory Hyperpigmentation
Tranexamic AcidABSTRACT The risk of post-inflammatory hyperpigmentation (PIH) in patients undergoing dermatologic procedures is well known. It is especially common after laser procedures and chemical peels but can be seen with any procedure. PIH is also a sequela of acne, burns, and other trauma. High-risk patients are thought to have excessive production and abnormal distribution of melanin within the skin tha …
Tranexamic Acid
The Pinch Stitch: A Pearl for Suturing Wounds Under Tension
pinch stitchClosing defects under tension in areas such as the scalp and back may be challenging during dermatologic surgery. Different techniques have been advocated to ease the placement of the first deep suture under tension, including the slip-knot stitch, pully stitch, horizontal mattress suture, pulley set-back dermal suture, and tandem pulley stitch. INTRODUCTION Closing defects under tension in …
pinch stitch
Severe Oral Mucositis: A Rare Adverse Event of Pembrolizumab
Oral MucositisTreatment of malignancy with anti-programmed cell death 1 (PD-1) immune checkpoint inhibitors can cause mucocutaneous side effects resulting from T cell activation. Due to their recent development, the full side effect profile remains to be fully elucidated, however dermatologic adverse events are most common. The main oral toxicities of these immune checkpoint inhibitors include: xerostomia, dysg …
Oral Mucositis
Rapidly Enlarging Malignant Proliferating Trichilemmal Tumor
Trichilemmal Tumor Malignant proliferating trichilemmal tumors are rare adnexal neoplasms that most commonly occur on the scalp in elderly women. These tumors are associated with recurrence and even nodal or distant metastatic spread. Here, JDD authors describe a 38-year-old patient who presented with a scalp nodule that was diagnosed as a high-grade malignant proliferating trichilemmal tumor. Introduction Th …
Trichilemmal Tumor