Graham-Little-Piccardi-Lasseur Syndrome: A Case Report
alopeciaINTRODUCTION Graham-Little-Piccardi-Lasseur Syndrome (GLPLS) is a rare clinical subtype of lichen planopilaris (LPP) that manifests as a triad of scarring alopecia of the scalp, nonscarring alopecia of the axillary and the pubic skin, and widespread lichenoid follicular papules.1 GLPLS more commonly affects women (male-to-female ratio ≃ 1:4), with the classic patient being a middle-aged Ca …
alopecia
Severe Psoriasis Presenting in 3-Year-Old Child With Nail Dystrophy
psoriasis Severe Psoriasis Presenting in 3-Year-Old Child With Nail Dystrophy: Response to Biologic Treatment Danielle Rinck MDa, Elaine Siegfried MDb aBeth Israel Deaconess Medical Center, Boston, MA | bSaint Louis University School of Medicine, St. Louis, MO J Drugs Dermatol. 2022;21(8):897-899. doi:10.36849/JDD.6888   A previously healthy 3-year-old boy presented to our Pediatric Derm …
psoriasis
Reversible Hair Loss in Lichen Planopilaris | Great Cases from the JDD
LICHEN PLANOPILARISINTRODUCTION Lichen planopilaris (LPP) is a cicatricial alopecia that presents with patchy or diffuse hair loss at the vertex or parietal scalp. Although there is no gold standard therapy, most interventions are immune modulating and aimed at reducing inflammation and terminating the scarring process to prevent further fibrosis.3 Even amongst patients who respond to therapy, hair loss at alopeci …
LICHEN PLANOPILARIS
The “Flolan Rash” | Great Cases from the JDD
Flolan RashINTRODUCTION Epoprostenol (Flolan) is a last-resort intravenous (IV) medication for the treatment of severe pulmonary arterial hypertension (PAH). Cutaneous adverse events of Flolan are well-known by pulmonologists, though lacking in dermatologic literature.1 We report an extensive near erythrodermic appearing asymptomatic eruption following long-term use of epoprostenol. This characteristic and …
Flolan Rash
Refractory Alopecia Areata and Vitiligo Responding to Tofacitinib Monotherapy
Tofacitinib INTRODUCTION Tofacitinib is a Janus kinase (JAK) 1-3 inhibitor first U.S. Food and Drug Administration (FDA) approved in 2012 for rheumatoid arthritis, with subsequent approval for psoriatic arthritis, ulcerative colitis, polyarticular course juvenile idiopathic arthritis, and ankylosing spondylitis in 2017, 2018, 2020, and 2021, respectively.1,2 In the last several years, oral tofacitinib …
Tofacitinib