Scaly Papules – Friday Pop Quiz 3/31/2023

A 55-year-old patient from the Caribbean presents with indurated scaly papules and plaques on his trunk, arms, and legs. The rash started six months ago and has progressed rather quickly. Review of system was notable for pruritus and xerosis; patient reported no personal history of skin diseases, including psoriasis and atopic dermatitis. Several 4-mm punch biopsies were performed. Based on the history and images, which of the following histologic findings are the most sensitive and specific for this disease?

A. Low CD3(+) cells in the atypical T-cell infiltrate

B. Low CD4(+) cells in the atypical T-cell infiltrate

C. Loss of CD7 expression in the atypical T-cell infiltrate

D. Many CD8(+) cells in the atypical T-cell infiltrate

E. Many CD30(+) cells in the atypical T-cell infiltrate

To find out the correct answer and read the explanation, click here

 

Brought to you by our brand partner