hyperkeratotic plaques

The Many Faces of Psoriasis | Part 1
psoriasis
by Olabola Awosika, MD, MS, FAAD on
Psoriasis affects 2% of the world’s population and occurs in a bimodal distribution, peaking in early and late adulthood. Chronic plaque psoriasis is the most common variant and presents as well demarcated erythematous plaques with prominent white scale on the scalp and extremities. The erythema of psoriasis varies across the spectrum of skin tones, ranging from a salmon and deep reddish …
Hand Foot Skin Reaction Associated With Palbociclib
Palbociclib
by NEXT STEPS IN DERM TEAM on
INTRODUCTION Palbociclib is one of three new small-molecule inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) approved for use in the treatment of hormone receptor positive (HR+) and human epidermal growth factor receptor 2 negative (Her2-) advanced or metastatic breast cancer. CDK4/6 inhibitors have a good overall safety profile but reported side effects include cytopenias, diarrhea, QTc pr …