Tranexamic Acid Therapeutic Cheat Sheet
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX …
Tranexamic acid (TXA) is a synthetic lysine derivative that reversibly blocks the lysine-binding site on plasminogen, preventing conversion to plasmin. While originally developed as an antifibrinolytic agent to reduce bleeding, TXA has several downstream effects that make it useful in dermatology, particularly for pigmentary disorders, with emerging evidence in inflammatory disorders as well. TX … 
Tranexamic acid is one of the latest therapies for treating melasma, and one that’s most commonly prescribed for women. An editorial published in the April issue of the Journal of Drugs in Dermatology encourages dermatology clinicians to also consider the effect melasma has on men and to utilize tranexamic acid as a treatment option.
I interviewed the authors, dermatologist and Mohs surgeon A …