A 62-year old patient was admitted for new-onset shortness of breath secondary to pneumonia. Dermatology was consulted to evaluate a pruritic skin eruption affecting multiple body sites. She denied prior skin problems, and antihistamines failed to improve the itch. The patient also denied muscle weakness, myalgia and arthralgia.

Based on the clinical images, which of the following is the next best step in the management of this patient?

A. Creatine kinase (CK), aldolase

B. Serum IgE levels

C. Serum tryptase levels

D. Basic metabolic panel (BMP), liver function test (LFT)

E. Bone marrow biopsy

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