IL-23 inhibitors

Successful Use of Tildrakizumab for Treatment of Palmoplantar Pustulosis
Palmoplantar Pustulosis
by NEXT STEPS IN DERM TEAM on
Palmoplantar pustulosis (PPP) is a rare, recurrent skin disorder that presents a major challenge to clinical therapy. JDD author Danilo C. Del Campo, MD, FAAD reports a case of a 69-year-old woman with a 20-year history of psoriasis with skin manifestations and clinical and pathologic features consistent with PPP. After intolerance to apremilast and unsuccessful use of topical corticosteroids and …
IL-23 Inhibitors for Psoriasis Therapeutic Cheat Sheet
IL-23 Inhibitors
by Blair Allais, MD on
Psoriasis involves a complex inflammatory cascade mediated by various cytokine effectors. Over the past fifteen years, treatment options have evolved to include biologic medications that provide targeted inhibition of various pathways. IL-23 has emerged as an important inflammatory cytokine in the pathogenesis of psoriasis. We continue our series, Therapeutic Cheat Sheet, with a closer look at IL- …