Pregabalin for Chronic Pruritus | Therapeutic Cheat Sheet
Chronic pruritus affects 8-16% of the general population and has a profound impact on patient quality of life.1-3Although the symptom of pruritus may originate from a number of underlying etiologies, including metabolic derangements and infectious causes, along with neoplastic, inflammatory, or psychiatric conditions, other cases may be idiopathic in nature.4 Given the diversity of underlying cont …
Chronic pruritus affects 8-16% of the general population and has a profound impact on patient quality of life.1-3Although the symptom of pruritus may originate from a number of underlying etiologies, including metabolic derangements and infectious causes, along with neoplastic, inflammatory, or psychiatric conditions, other cases may be idiopathic in nature.4 Given the diversity of underlying cont … Continue reading "Pregabalin for Chronic Pruritus | Therapeutic Cheat Sheet"
Gabapentin is a well-established treatment option for itch with a reassuring safety profile that does not require continued lab monitoring. Generalized itching is a common cause of visits to the dermatologist and can be difficult to treat, leading to sleepless nights and inability to function. We continue our series, Therapeutic Cheat Sheet, with a closer look at gabapentin.
GABAPENTIN THERAPEUT … 
Atopic dermatitis (AD) is a common skin condition characterized by pruritus and occurs as a result of factors related to impaired skin barrier and immune response, as well as environmental and infectious agents. Patients with poor control on topical therapy are looking for safe and effective systemic treatments. We continue our series, Therapeutic Cheat Sheet, with a closer look at dupilumab, whic … 
Authors Ross Tanis MD MS, Katalin Ferenczi MD, and B Michael Payette MD MBAB present a case where they demonstrated that treatment of Prurigo Nodularis (PN) with dupilumab significantly decreased pruritis and the size and number of new lesions after 2 months of treatment.
INTRODUCTION
Prurigo nodularis is an intensely pruritic skin disease in which dome-shaped papulonodules result from chroni … 