Friday Pop Quiz 8/14/2026
A 70-year-old female presents for treatment of a large tumor shown on her face. It has been increasing in size for over 10 years. Which of the following medication is FDA approved for locally advanced basal cell carcinoma that is not amenable to surgical therapy?
A. Ipilimumab
B. Sonidegib
C. Erolitinib
D. Interferon alpha
E. 5-fluorouracil
To find out the correct answer and re …
A 70-year-old female presents for treatment of a large tumor shown on her face. It has been increasing in size for over 10 years. Which of the following medication is FDA approved for locally advanced basal cell carcinoma that is not amenable to surgical therapy?
A. Ipilimumab
B. Sonidegib
C. Erolitinib
D. Interferon alpha
E. 5-fluorouracil
To find out the correct answer and re … 
In the age of immunotherapy, is there a place for hedgehog inhibitors in cutaneous oncology?
ODAC Guest Advisor Dr. Vishal Patel says hedgehog inhibitors are even more important now. Dr. Patel spoke with Next Steps in Derm, in partnership with the ODAC Dermatology Conference, where he outlined scenarios in clinical treatment where hedgehog inhibitors make sense. Learn about the two approved m … 
Basal cell carcinoma (BCC) is the most common human cancer. When curative surgery and radiotherapy are contraindicated, systemic agents targeting the hedgehog signaling pathway are invaluable options for this subset of adult patients with locally advanced BCC (laBCC). Vismodegib and sonidegib are oral options with similar efficacy and side effect profiles. With the absence of head-to-head comparis … 
On this Mnemonic Monday, we challenge you to remember the side effects of hedgehog inhibitors, vismodegib and sonidegib, with the following mnemonic:
MAD Weight loss
M=muscle spasm (72% of cases)
A=alopecia (64% of cases)
D= dysgeusia (55% of cases)
Weight loss= weight loss (45% of cases)
Click HERE to download or print your mnemonic card.
Study More!
Need a refresher on he …