A 2-year-old male with recurrent flares of the pictured findings developed non-tender nodules on his bilateral thighs. What would likely establish the diagnosis?

A. Genetic testing for STAT3 and DOCK8 mutations

B. Genetic testing for SPINK5 mutations

C. Obtaining immunoglobulin E levels

D. Obtaining serum zinc levels

E. Flow cytometry to evaluate CD18 expression

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