The patient had an extensive superficial basal cell carcinoma on the forehead treated with topical imiquimod and returned 4-weeks later with this reaction. Which cytokine is not activated by this medication?

A. Tumor necrosis factor (TNF)-α
B. Interferon (IFN)-α
C. Interferon (IFN)-γ
D. Interleukin (IL)-12
E. Interleukin (IL)-4

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