Pathogenesis of Pruritus – Friday Pop Quiz 12/1/2023
An increased level of which of the following proteins is most implicated in the pathogenesis of pruritus in the patient’s condition?
A. Defensin
B. Histamine
C. Interleukin-2
D. Interleukin-31
E. Transforming growth factor-beta
To find out the correct answer and read the explanation, click here.
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An increased level of which of the following proteins is most implicated in the pathogenesis of pruritus in the patient’s condition?
A. Defensin
B. Histamine
C. Interleukin-2
D. Interleukin-31
E. Transforming growth factor-beta
To find out the correct answer and read the explanation, click here.
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Increased expression of which of the following is most associated with the patient’s condition?
A. Interferon-gamma
B. Interleukin-2
C. Interleukin-13
D. Transforming growth factor-beta
E. Tumor necrosis factor-alpha
To find out the correct answer and read the explanation, click here.
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Ruxolitinib (OPZELURA) is a twice daily topical cream that is FDA approved for non-segmental vitiligo and mild to moderate atopic dermatitis1. JAK inhibitors are a class of drugs effective in treating a wide variety of inflammatory conditions. Initially only FDA approved for non-dermatologic conditions such as rheumatoid arthritis and ulcerative colitis, there is now strong evidence that JAK/STAT … 
Infection by which of the following organisms is most likely to be present in the patient’s condition?
A. Cutibacterium acnes
B. Herpes simplex virus
C. Poxvirus
D. Staphylococcus aureus
E. Streptococcus agalactiae
F. Streptococcus pyogenes
To find out the correct answer and read the explanation, click here.
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Intravenous immune globulin (IVIG) is a concentrate of pooled immunoglobulins derived from plasma donors. Its unique mechanism of action expands the utility of the medication to a variety of conditions. We continue our series, Therapeutic Cheat Sheet, with a closer look at IVIG, which is FDA-approved for the treatment of dermatologic conditions including dermatomyositis, Kawasaki disease, ITP, and …