biologics

Tumor Necrosis Factor (TNF) Inhibitors Therapeutic Cheat Sheet
TNF inhibitors for psoriasisWith the advent of biologics, patients with moderate-to-severe plaque psoriasis have experienced increased control of disease and improved quality of life. Tumor necrosis factor (TNF) inhibitors are some of the earliest biologics prescribed for psoriasis, psoriatic arthritis and, more recently, hidradenitis suppurativa. In this month’s installment of Therapeutic Cheat Sheets, we discuss TNF inhi …
TNF inhibitors for psoriasis
Methotrexate Therapeutic Cheat Sheet
Methotrexate injection for psoriasisIn this month’s installment of Therapeutic Cheat Sheet, we will review methotrexate and its use in dermatology. Methotrexate has been utilized as therapy for psoriasis and many other dermatologic conditions since its approval by the FDA in 1972.1 While an effective systemic agent for a multitude of dermatologic and non-dermatologic diseases, prescribers should be aware of the side effect profile …
Methotrexate injection for psoriasis
Inhibiting the JAK/STAT Pathway to Treat Inflammatory Skin Diseases
JAK InhibitorsNext Steps in Derm, in partnership with ODAC Dermatology, Aesthetic and Surgical Conference, interviewed Dr. Jonathan Zippin, Vice-Chair of Research and an Associate Attending Dermatologist and Associate Professor of Dermatology at Weill Medical College of Cornell, and Director of the Contact, Occupational and Photodermatitis Service. Watch as he reviews the JAK/STAT signaling pathway in normal i …
JAK Inhibitors
Hydroxychloroquine, Pentoxifylline, and Colchicine: Off-Label is ON in Dermatology
Hydroxychloroquine, Pentoxifylline, and Colchicine: Off-Label is ON in Dermatology!So many diseases, so few FDA approved indications. Between the mind-numbing time and cost from bench to bottle, it is no surprise that dermatologists, as masters of the integument are the off-label bandits, marrying their wealth of knowledge on the pathophysiology of skin diseases to the mechanisms by which medications work to create an evidenced-based armament of therapies for both common and rar …
Hydroxychloroquine, Pentoxifylline, and Colchicine: Off-Label is ON in Dermatology!
Controversies in Pediatric Dermatology: Systemic Therapies
Controversies in Pediatric DermatologyDr. Yasmine Kirkorian, Interim Chief of Dermatology at Children's National Health System and Assistant Professor of Dermatology and Pediatrics at the George Washington School of Medicine & Health Sciences, summarizes recent controversies in the field of pediatric dermatology regarding the usage of systemic therapies in children. This article will provide an overview of the following: …
Controversies in Pediatric Dermatology