Novel Therapeutics in Atopic Dermatitis
Atopic dermatitis (AD) is a chronic inflammatory skin disease. The pathogenesis of AD is complex with many mediators involved and can be broken down into 4 categories:
Immune dysregulation
Abnormal skin barrier
Abnormal itch/scratch cycle
Abnormal skin microbiome
In AD, there is a breakdown in molecular control of the immune system, leading to overproduction and expressi …
Atopic dermatitis (AD) is a chronic inflammatory skin disease. The pathogenesis of AD is complex with many mediators involved and can be broken down into 4 categories:
Immune dysregulation
Abnormal skin barrier
Abnormal itch/scratch cycle
Abnormal skin microbiome
In AD, there is a breakdown in molecular control of the immune system, leading to overproduction and expressi … 
When we think about skin, a few things come to mind: protection, temperature regulation, sensation. However, there is growing interest in the microbiome of the skin. Our skin flora can be likened to an invisible ecosystem. Similar to fingerprints, it is unique to each individual. The complexity of the skin microbiome is continuing to be researched. This research is paving the way to improve our un … 